Butabarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of CYP3A4 inducers may possibly lessen sufentanil concentrations and efficacy, potentially precipitating withdrawal syndrome in sufferers who may have formulated Bodily dependence to sufentanil. Discontinuation of concomitantly ... https://michaels134mop8.angelinsblog.com/profile