An extensive literature evaluate of research among 1995 and 2018 was carried out using the Digital databases PubMed and EBSCO Host. Lookups were done employing the following conditions: full knee arthroplasty (TKA); cyclooxygenase-2 inhibitors; bracing; physical therapy; weight loss; knee; treatment; therapeutics; OA; intra-articular injection; hyaluronic acid; corticosteroid; and opt... https://www.theorthopaedicandpainpractice.com/non-surgical-treatments-for-knee-joint-pain/