two. Histamine Receptor Antagonism: Some sedatives, such as antihistamines, exert their sedative effects by blocking histamine receptors within the brain, specially H1 receptors. Histamine plays a job in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness. Don’t blend sedatives with each other or with other remedies https://wayloneasiz.free-blogz.com/80340237/sedative-medications-in-icu-their-roles-effects