Without a doubt, TERT phosphorylation is shown being needed for telomerase activation. b Outcome of BETi on telomere regulation. BETi compete with acetylated histones for that binding on the BRD4 bromodomains releasing BRD4 from brief telomere, destabilizing telomere security complex Group and lowering Telomerase activity. The progressive shortening of telomere https://zanezlwhq.angelinsblog.com/31188568/the-ultimate-guide-to-jq-1-mechanism-of-action