At this time, There are 2 kinds of scientific studies on itaconate: Irg1−/− macrophages and also the regulatory outcome of itaconate derivatives. Both of these final results were complementary and revealed the regulatory mechanisms of itaconate associated alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription issue 3 https://foy25155432.link4blogs.com/51758442/e-daporinad-fundamentals-explained